ISO Standard Analyzes Nano-Objects Using Asymmetrical-Flow and Centrifugal Field Flow Fractionation

In June 2018, the International Standardization Organization (ISO) published standard ISO/TS 21362:2018, “Nanotechnologies — Analysis of nano-objects using asymmetrical-flow and centrifugal field-flow fractionation.”  The document identifies parameters and conditions, as part of an integrated measurement system, necessary to develop and validate methods for the application of asymmetrical-flow and centrifugal field-flow fractionation to the analysis of nano-objects and their aggregates and agglomerates dispersed in aqueous media.  According to ISO, in addition to constituent fractionation, analysis can include size, size distribution, concentration, and material identification using one or more suitable detectors.  The standard provides general guidelines and procedures for application, and specifies the minimal reporting requirements necessary to reproduce a method and to convey critical aspects.