On July 11, 2016, the NanoSafety Cluster (NSC) published the 2016 edition of the Compendium of Projects in the European NanoSafety Cluster. According to NSC, the focus of investment and research “has moved increasingly towards predictive and high throughput approaches to nanosafety, including safety-by-design, bioinformatics, as well as the utilisation of nano-characterisation and safety datasets to support regulation and nanoproduct commercialisation.” The 2016 Compendium contains entries from nine running Seventh Research Framework Program (FP7) projects, and 11 Horizon 2020 projects (seven running and four in negotiations), offering “exciting insights” into the state-of-the-art collaborative research occurring across Europe. The Compendium also includes updates from the NSC Working Groups (WG) and provides introductions to two new WGs — Safety by Design (WG9) and the Industrial Innovation Liaison (WGi2L/WG10). According to the Compendium, it intends to bring the research community closer together and show the potential for synergy. To establish links and communication between researchers well before the publication of their results, the Compendium focuses on the projects’ strategic aims, covers specific work objectives and the methods used in research, and documents human capacities and partnerships.