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On April 12, 2020, the World Health Organization (WHO) published Environmental Health Criteria 244:  Principles and methods to assess the risk of immunotoxicity associated with exposure to nanomaterials.  WHO states that the document presents an overview of the current knowledge and evidence on principles and basic mechanisms of immunotoxicity caused by engineered nanomaterials (ENM). …

On May 4, 2020, the U.S. Environmental Protection Agency (EPA) published proposed significant new use rules (SNUR) under the Toxic Substances Control Act (TSCA) for chemical substances that were the subject of premanufacture notices (PMN) and are subject to orders issued by EPA pursuant to TSCA.  85 Fed. Reg. 26419.  The SNURs require persons who…

On April 7, 2020, the European Union (EU) Observatory for Nanomaterials (EUON) published a Nanopinion entitled “Carbon Nanotubes — First nanomaterial of high concern on the SIN List.”  As reported in our November 27, 2019, blog item, ChemSec added carbon nanotubes to the Substitute It Now (SIN) List in November 2019.  According…

The International Organization for Standardization (ISO) has published standard ISO/TS 11308:2020, “Nanotechnologies — Characterization of carbon nanotube samples using thermogravimetric analysis.”  The standard provides guidelines for the characterization of carbon nanotube (CNT)-containing samples by thermogravimetric analysis (TGA), performed in either an inert or oxidizing environment.  The standard offers guidance on the purity assessment…

On December 5, 2019, the National Toxicology Program (NTP) announced that the NTP Technical Report on the Toxicity Studies of 1020 Long Multiwalled Carbon Nanotubes Administered by Inhalation to Sprague Dawley (Hsd:Sprague Dawley® SD®) Rats and B6C3F1/N Mice is now available.  In 2003, the Rice University Center for Biological and Environmental Nanotechnology…

As reported in our February 1, 2019, blog item, the American Conference of Governmental Industrial Hygienists (ACGIH®) Threshold Limit Values for Chemical Substances (TLV®-CS) Committee included carbon nanotubes on its 2019 list of chemical substances and other issues under study.  Being placed on the under study list indicated that the…

On October 3, 2017, the U.S. Environmental Protection Agency (EPA) promulgated a final significant new use rule (SNUR) under Section 5(a)(2) of the Toxic Substances Control Act (TSCA) for the chemical substance identified generically as bimodal mixture consisting of multi-walled carbon nanotubes (MWCNT) and other classes of carbon nanotubes (CNT), which was the subject of…

The National Institute for Occupational Safety and Health (NIOSH) has published a chapter in the fifth edition of the NIOSH Manual of Analytical Methods (NMAM) entitled “Analysis of Carbon Nanotubes and Nanofibers on Mixed Cellulose Ester Filters by Transmission Electron Microscopy.”  The draft chapter provides standardized approaches for the analysis of carbon nanoparticles. …

The International Agency for Research on Cancer (IARC) announced on May 19, 2017, publication of Volume 111 of the IARC Monographs, Some Nanomaterials and Some Fibres.  The Monograph contains evaluations of the carcinogenic hazard to humans of fluoro-edenite fibrous amphibole, silicon carbide fibers and whiskers, and carbon nanotubes.  As reported in our November 3,…

The National Institute for Occupational Safety and Health (NIOSH) recently announced the availability of the following publications:

  • Nanotechnology: Delivering on the Promise is a two-volume American Chemical Society symposium report that discusses advances in nanotechnology and the value of precautionary risk management.  Editors include NIOSH Associate Director for Nanotechnology Charles L. Geraci, Ph.D., CIH.  Lynn

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