Environmental Health Perspectives

The November 1, 2007, issue of Environmental Health Perspectives (EHP) includes a research article and meeting report concerning nanomaterials. The research article, entitled “Nanosize Titanium Dioxide Stimulates Reactive Oxygen Species in Brain Microglia and Damages Neurons in Vitro,” describes the in vitro neurotoxicity of P25, a commercially available titanium dioxide nanomaterial. According to the study, P25 appears to be non-toxic to isolated N27 neurons, but stimulates BV2 microglia to produce reactive oxygen species and damages oxidative stress-sensitive neurons in cultures of brain striatum. The meeting report, entitled “Meeting Report: Hazard Assessment for Nanoparticles — Report from an Interdisciplinary Workshop,” presents the findings from a nanotoxicology workshop held on April 6-7, 2006, at the Woodrow Wilson International Center for Scholars. Meeting attendees addressed two questions: what information is needed to understand the human health impact of engineered nanoparticles, and how this information is best obtained.
Continue Reading EHP Publishes Research Article and Meeting Report on Nanomaterials

On August 3, 2007, EHP-in-Press posted an article entitled “Nanosize Titanium Dioxide Stimulates Reactive Oxygen Species in Brain Microglia and Damages Neurons, In Vitro.” The article describes the in vitro neurotoxicity of P25, a commercially available titanium dioxide nanomaterial. According to the study, P25 appears to be non-toxic to isolated N27 neurons, but stimulates BV2