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The February 2019 issue of Computational Toxicology includes an article entitled “Grouping of multi-walled carbon nanotubes to read-across genotoxicity:  A case study to evaluate the applicability of regulatory guidance.”  The article describes a case study, performed by scientists at the European Commission’s (EC) Joint Research Center (JRC), to explore and illustrate read-across of genotoxicity data by following the “Recommendations for nanomaterials applicable to the Guidance on...

The European Commission’s (EC) Joint Research Center (JRC) published on February 13, 2019, a report entitled An overview of concepts and terms used in the European Commission’s definition of nanomaterial.  The report supports the implementation of the EC’s Recommendation on a definition of nanomaterial (2011/696/EU).  It addresses the definition’s key concepts and terms and discusses them in a regulatory context.  Corresponding to the broad scope of the definition, the report states...

On November 5, 2018, the European Commission’s (EC) Joint Research Center (JRC) announced the availability of the NANoREG Toolbox, an inventory of publicly available tools for the safety assessment of nanomaterials.  As reported in our October 5, 2017, blog item, JRC first published the inventory as a Microsoft Excel®-based dataset.  JRC scientists have now published an article, “An inventory of ready-to-use and publicly available tools for the safety assessment of nanomaterials,”...

The European Commission (EC) Joint Research Center (JRC) posted a report on the October 5-6, 2017, “NanoReg2 Regulatory Preparedness for Innovation in Nanotechnology Workshop.”  Regulatory preparedness was defined at the workshop as the regulators’ timely awareness of innovations and the regulators’ actions to check whether present legislation covers all safety aspects of each innovation, including initiating revision of the legislation as appropriate.  Achieving...

On September 12-13, 2018, the Organization for Economic Cooperation and Development (OECD), NanoReg2, and GRACIOUS hosted a “Scientific Workshop:  Grouping of Nanomaterials.”  The Workshop brought together 120 nanotechnology specialists from Europe, North America, and Asia to discuss a bottleneck in nanomaterials development and testing.  The agenda and the following slides from the workshop have been posted online:...

On September 21, 2018, the Organization for Economic Cooperation and Development (OECD) announced four new case studies on integrated approaches for testing and assessment (IATA), including a Case Study on Grouping and Read-Across for Nanomaterials — Genotoxicity of Nano-TiO2.  The European Union (EU) Joint Research Center (JRC) developed the case study for the genotoxicity of nano-titanium dioxide (TiO2) for illustrating the practical use of IATA.  The case study applies the...

The European Commission’s (EC) Joint Research Center has published a Technical Report entitled Mapping Nanomedicine Terminology in the Regulatory Landscape.  According to the abstract, to support a better understanding of terms used in the regulatory domain, the Nanomedicines Working Group of the International Pharmaceutical Regulators Forum (IPRF) prioritized the need to map, compile, and discuss the currently used terminology of regulatory scientists coming from different geographic...

As reported in our February 16, 2018, blog item, the European Commission (EC) Joint Research Center (JRC) has opened a call to access its Nanobiotechnology Laboratory.  The Nanobiotechnology Laboratory features state-of-the-art equipped facilities designed to foster interdisciplinary studies.  Offering access to the Nanobiotechnology Laboratory is part of JRC’s strategy to enhance dissemination of scientific knowledge; boost competiveness; bridge the gap between...

The European Commission (EC) Joint Research Center (JRC) has opened a call to access its Nanobiotechnology Laboratory.  The Nanobiotechnology Laboratory features state-of-the-art equipped facilities designed to foster interdisciplinary studies, with a special emphasis on the characterization of nanomaterials, nanomedicines, advanced materials and their interactions with biological systems, as well as on the detection, identification, and characterization of nanomaterials in food...

The European Commission (EC) Joint Research Center (JRC) has published the NANoREG Toolbox for the Safety Assessment of Nanomaterials.  As reported in our May 8, 2017, blog item, JRC previously published a Science for Policy report entitled NANoREG framework for the safety assessment of nanomaterials.  The report was developed within the NANoREG project, “A common European approach to the regulatory testing of nanomaterials.”  The NANoREG framework represents the project’s proposal...